alcuni elementi per capire la posizione etnorazziale degli andamanesi, popolazioni colpite duramente dal recente maremoto:
The DNA – A Tell-Tale of the Vanishing Human Populations: Who are they? Where they came from? Do they hold the key to the mystery of our own origins?
The Andaman and Nicobar Group of Islands
This group of islands consists of 319 small islands with a total area of 8293 sq.kms. spread over a length of 700 kms and the breadth of 250 kms. It is situated about 1255 kms from Kolkata, 193 kms South of Burma, and 1191 kms from Chennai (Madras). On a cluster of these islands deep in the Bay of Bengal lives a group of people who have locked themselves away from the modern world. For centuries, they gave a fierce fight to anyone who tried to intrude their land and privacy. Marco Polo called them Cannibals. In their struggle of survival, they had major encounters with outsiders such as in 1789, when Lieutenant Archibald Blair arrived at Chatoam Island, their settlement was shifted to Port Cornwallis in 1792 and was abandoned in 1794. Their origins are really a mystery. No one knows where they came from? How long they have been there? Could these islanders hold the key to the mystery of our own origins? Their world could serve as a window to look into the past showing us how were we hundred thousand years ago when the first modern humans left Africa. The Andaman and Nicobar islands became the property of India when British left India in 1947. Ruled now from Delhi, they are part of the territory of the Republic of India with local administrative head quarters at Port Blair in Andamans.
Last and probably the vanishing
The native inhabitants of the Andaman islands of the Indian ocean are one of the seve-
ral isolated groups of small statured hunter-gatherers sometimes known as “Negritos”,
who survived in isolated parts of Asia. They share physical features such as short
stature, dark skin, peppercorn hair, scant body hair and sometimes steatopygia with
African pygmies and other Asian Negrito people. Andamanese Crania resemble very
closely to those of Africans. Due to their violent resistance to the foreign intrusions, they earned the reputation for ferocity. They remained completely isolated from the world until the establishment of a British Penal Settlement in the islands, after the Indian mutiny of 1857. The British befriended one of the tribes, the Great Andamanese and employed them as bush police to recapture escaped convicts. The Great Andamanese suffered colonialism and in the 19 centuries, their number collapsed from several hundred to a few dozen individuals. The ancient tribes of Andaman and Nicobar islands have always mystified explorers and scientists, how and when they came to these islands is a puzzle. Many believe that they might have been washed ashore of islands hundreds of years ago from a slave ship. Of the dozen linguistically distinct tribes who populated the islands, several of them have vanished and there is not even a single representative of some of them. The four groups which survived are the Jarawa, the Great Andamanese, the Onge and the Sentinelese. The family of Andamanese languages is totally distinct and, as we know, it is not related to any language outside the Andaman islands. It is very different from the languages spoken in the old world in Africa and Eurasia; this may indeed represent a linguistic relic of what South-East Asia may have looked like.
Intriguingly, Andamanese languages have grammatical and lexical affinities to the language spoken by the Kusunda, a isolated Nepalese ethnic group with the only language of the Asian mainland, which is thought to belong to the Indo-Pacific phylum. Philologists have not yet succeeded in connecting them to any recognized family of speech. Abstract ideas are expressed in this language by the free use of gestures.
The Jarawas
The number of Jarawas in 1977 census was estimated to be 275; the present estimate indicates that it has been reduced to 200. They eat fruits and tubers, white pig and monitor lizard. Though deer are plentiful in the forest area reserved for the Jarawas, they have not taken to eating venisons, for reasons unknown. They do not hunt birds; they, however, do fishing with bows and arrows. Shifted from their original homes, they now reside on the Northeastern coast of Middle and South Andamans, hemmed in by the Andaman Trunk Road which, since 1970s, have cut them off from hunting grounds and fresh water supplies.
The Great Andamanese
The Great Andamanese, also known as South Andamanese were the people who first came into conflict with the colonial authority during the Penal Settlement founded in 1858. The tribes organized a well planned attack on the Port Blair settlement in 1859 and caused significant damage to this settlement in spite of the betrayal an escaped convict Dudhnath Tiwari on the eve of attack. Dudhnath
Tiwari who had lived with the tribals for several months was a sepoy of the 1857 mutiny. In turn, the Great Andamanese also suffered heavily as they were fighting only with bows and arrows against the guns and artillery of the colonial regime. This probably was the worst case of genocide in the colonial history of tribal encounters. Consequently, the estimated population of 3000-3500 tribals was drastically reduced. In 1906-1908 when Raddiffe-Brown worked on the Great Andamanese, their population was a bare 625. Since then, it was further declined to stand at 23 (14 males and 9 females). Raddiffe-Brown collected from the tribals hair samples, which are now part of the Duckworth collection, University of Cambridge, UK. Their present number is only 36.
The Onges are one of the most primitive and vanishing tribes of India. Their present number is only 98. They belong to Negrito racial stock and have been relegated to the reserved pockets both at Dugong Creek and South Bay of Little Andaman Island. They are diminishing in number. Earlier, they were fully dependent on the food from the sources provided by nature; however, there is now a settlement in which food is provided by the Govt. of India.
The Sentinelese are the inhabitants of the North Sentinel Island situated in the West of the South Andaman covering an area of 60 sq. kms. They are probably the world’s only Paleolithic people surviving today without any contact with any other groups or community. They are considered to be an off-shoot of the Onge and the Jarawa tribes; however they have lost contacts with these main tribes and have acquired a different identity due to their habitation in isolation. The Sentinelese are very hostile and never leave their island; thus, very little is known about them. Their present number is estimated to be 250.
The inhabitants of Nicobar known as the Nicobarese belong to the same race of people as those who formerly lived on the seashore of Sumatra. Many a scholars have traced their origin either in Malaysia, Indonesia or Burma. The number of Nicobarese is about 22,000. The Nicobarese are Mangoloid tribe. There is another group of people, the Shompenese who live in Great Nicobar, the largest of the Nicobar group of Islands. Like the Nicobarese, they are also Mongoloid. The number of Shompenes is about 180
Why study tribal populations?
The origin of the Andamanese has been the subject of speculation for centuries. It is observed that the Andamanese are near extinction following the population reduction caused by “pacification” and disease. Thus, the studies on tribal populations need to be aimed at mainly two objectives, (1) to understand the mystery of our own origins and to understand the origin and history of people of India, and (2) to understand the genetic basis of complex diseases.
To better understand the genetic basis of complex genetic diseases in both tribals and non-tribals, it is important to study genetic diversity in tribal populations. Such studies will be all the more important if common diseases turn out to be caused by common susceptibility alleles that are likely to be old and, therefore, present in tribal populations. If this does not turn out to be true, and where many less frequent and possibly population-specific alleles predispose to diseases, it would be useful to examine possible susceptibility alleles in different populations. The demographic history and genetic diversity in tribal populations of India make tribal studies particularly informative for the fine mapping of complex genetic diseases. Furthermore, many of the environmental risk-factors that may be responsible for triggering certain complex diseases may not be common in tribals; thus, in such cases, it would be more feasible to differentiate genetic factors from environmental risk-factors for these diseases. As environmental risk-factors, are known to be associated and are prevalent with urban and more sedentary lifestyles, it is imperative that we study the genetic diversity among Indian tribal populations, particularly the primitive ones.
CCMB has undertaken a very large programme on the human genetic diversity in tribal and caste populations of India in collaboration with Anthropological Survey of India and MoU in this regard has been signed under which studies have already been initiated.
Existing models of modern human evolution
Based on the various evidences available from the past, there are three models of human evolution which have emerged out of the efforts of various research workers in the field.
The multiregional model
This model proposes that there was no single geographical origin for modern humans, but that after the radiation of Homo erectus from Africa into Europe and Asia ~ 0.8 – 1.8 million years before present (YrBP), there were independent transitions in regional populations from Homo erectus to Homo sapiens. This model is supported primarily by the continuity of certain morphological traits in the fossil records (for example, the robust cheekbones observed in H. erectus fossils from South-East Asia and in modern Australian aborigines), which indicates that modern populations evolved over a very long period of time in the regions where they are found today. Simultaneous evolution from H. erectus to H. sapiens in dispersed populations could have been achieved through extensive gene flow among geographically diverse populations.
The Recent African Origin (RAO) model
RAO model proposes that all non-African populations descend from a H. sapiens ancestor that evolved in Africa 100,000 – 200,000 yrBP. These ancestors then spread throughout the world, replacing archaic Homo-populations (for example, the Neanderthals). This model is supported by fossil records, as the earliest modern human fossils were found in Africa and the Middle East, dating 90,000 – 120,000 yrBP. Recent molecular genetic evidences at present support this model. The RAO model predicts that all genetic lineages derive from a recent common African ancestor and that non-African populations should carry a subset of the genetic variations present in modern African populations.
The assimilation (or hybridization) model
The model proposes some gene flow between modern humans that migrated from Africa and archaic populations (for example Neanderthals) outside Africa. So, the evolution of modern humans could have been due to a blending of modern characters derived from African populations with local characteristics in archaic Eurasian populations. The present finding supports the ‘out-of-Africa’ theory.
Outcome of the present molecular genetic studies on Andaman and Nicobar islanders
The results based on the collaborative work of the organizations (mentioned elsewhere) is the first molecular genetic evidence on the affinities of the Andaman islanders, arguably the most enigmatic people on our planet. Mitochondria is the power-house of every cell of our body. However, the mitochondrial DNA (mtDNA) is a genetic element passed down only through women, while DNA of Y-chromosome is passed down to next generations only through men. Examination of the variation in DNA, technically known as DNA polymorphisms, provide new insights into the history of the Andamanese. Immigration of people can be tracked down based on the errors (known as mutations) made in the copying of DNA. These mutations slowly accumulate in certain regions of the DNA. Whenever a population splits and there is no inter-mingling of these splits, different populations accumulate different set of mutations, which depends upon the geographical location and the environment around them. Based on these mutations, it is possible to construct family trees of different lineages and shared geneology of human kind, and even approximately assign dates to the branch-points. Based on the mutations found in mtDNA, various groups (known as haplogroups) have been identified and several of these groups are specific to African populations. It has been suggested that one of the haplogroups, identified as M, is a genetic indicator of the migration of modern H. sapiens from Eastern Africa towards South-East Asia, Australia and Oceania. However, the analysis of the sites of mtDNA which essentially carry information for protein synthesis (also known as coding sites) indicate that Andamanese fall into sub-group of M not previously identified in any human population of the world including Africa and Asia and Andamanese split early from these populations. In the DNA from Y-chromosomes (passed down only through men as mentioned earlier) also various haplogroups have been identified. Amongst them D and E are characterized by the presence of a specific 350 bp longer piece of DNA in the Y-chromosome, which is designated as YAP+. YAP+ insertion mutation which probably originated in Africa and is virtually focused in sub-Saharan Africans but not present in Indian caste populations. However, this DNA is present in all the Andamanese (Negrito tribes). People having this DNA have other single base changes in the Y-DNA; all such changes have been further classified into various groups, which are called haplogroups. African YAP+ lineages are characterized by haplogroup E, whereas those in Asia are defined as haplogroup D. Further, two Asian YAP+ lineages have been observed in Asia. One has the M15 mutation which is common in Tibet, and the other has the M55 mutation common in Japan. The Onge and the Jarawa had neither of these mutations; thus, they are known to represent a sub-type of haplogroup D not described earlier
Studies of protein polymorphisms and of mitochondrial, Y-chromosomal, autosomal as well as X-chromosomal DNA variations indicate that African populations are the most variable and ancestral as expected under the RAO model described earlier. Phylogenetic analysis of mtDNA and Y-chromosomal haplotypes indicate that the most ancestral lineages are African-specific; and those of non-African lineages can be derived from a single ancestral African haplogroup, the results consistent with the RAO model. Therefore, it is clear that after an initial speciation event from H. erectus to modern H. sapiens, the humans spread across a broad geographical region and rapidly increased in population size in the past 50,000-100 thousand years.
The presence of a hitherto un-identified sub-set of the mtDNA Asian haplogroup M, and the Asian-specific Y chromosome group D, are consistent with the view that the Andamanese have closer affinities to Asian than African populations and therefore are the descendants of early paleolithic colonizers of South East Asia – the hunter gatherers and the first migrants moved out of Africa about 60,000-100 thousand years ago.
The questions remain, how then these so called Andamanese reached Andamans? And are there any tribes in Indian mainland which show resemblance with Andamanese and therefore shed light on the root of migration? To answer these questions, we also studied tribal population of the West coast of India. There are indeed tribes in Gujarat and Kerala which show close affinities to Andamanese Negrito tribes, both in their mtDNA haplotypes and Y-DNA halotypes (YAP+). These tribes appear to be older than the Andamanese. We have, therefore, undertaken DNA analysis of all the primitive tribes of India in collaboration with the Anthropological Survey of India (ASI). These studies may throw some light on the mystery of our own origins. In contrast to Andamanese, the Nicobarese have genetic affinities to groups widely distributed today throughout Asia; thus, the Nicobarese should presumably descend from Neolithic Agriculturists.
The study was supported by grants from -
Council of Scientific and Industrial Research (CSIR), Govt. of India to Dr. Lalji Singh; and Indian Council of Medical Research, Govt. of India to Dr. Lalji Singh, Dr. S. C. Sehgal, and Dr. V. R. Rao, with contributions from various agencies/individuals as follows:
Extraction and analyses of the hair DNA were performed by Erika Hagelberg at the ancient DNA Laboratory, University of Cambridge, U.K.
Blood samples were collected with the help of Dr. S. C. Sehgal, RMRC, Port Blair, India, after consultation with the Directorate of Tribal Welfare, the local administration, medical officer and with the consent of donors.
Genetic analysis of the DNA extracts from blood samples was performed at CCMB, Hyderabad, India
Transformed cell lines have been developed from most of the blood samples which are stored at CCMB, Hyderabad, India, and RMRC, Port Blair, India.
The findings titled “Genetic Affinities of the Andaman Islanders, a Vanishing Human Population” is published online in “CURRENT BIOLOGY” November 26, 2002 DOI: 10.1016/S0960982202013362 by Thangaraj et. al.
These results are an outcome of the collaborative work between scientists from the following organizations
Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India
Anthropological Survey of India, Nagpur, India
Regional Medical Research Centre, Port Blair, Andaman and Nicobar Islands, India
Department of Genetics, Stanford University, USA
Department of Biology, University of Oslo, Norway
Authors for Correspondence: Dr Lalji Singh , Dr K Thangaraj
http://www.ccmb.res.in/newccmb/andaman/mystery.html




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